The Genomic Formation of South and Central Asia
Gheesh Narasimhan
,
Nick Patterson
(1)
,
Priya Moorjani
(2)
,
Nadin Rohland
(3)
,
Nicole Boivin
(4)
,
Kumarasamy Thangaraj
(5)
,
Julio Bendezu-Sarmiento
(6)
,
David Reich
(1)
Gheesh Narasimhan
- Fonction : Auteur
Nicole Boivin
- Fonction : Auteur
- PersonId : 785580
- ORCID : 0000-0002-7783-4199
Kumarasamy Thangaraj
- Fonction : Auteur
- PersonId : 1043884
Julio Bendezu-Sarmiento
- Fonction : Auteur
- PersonId : 180705
- IdHAL : julio-cesar-bendezu-sarmiento
- ORCID : 0000-0002-0831-3955
- IdRef : 083321969
Résumé
By sequencing 523 ancient humans, we show that the primary source of ancestry in modern South Asians is a prehistoric genetic gradient between people related to early hunter-gatherers of Iran and Southeast Asia. After the Indus Valley Civilization’s decline, its people mixed with individuals in the southeast to form one of the two main ancestral populations of South Asia, whose direct descendants live in southern India. Simultaneously, they mixed with descendants of Steppe pastoralists who, starting around 4000 years ago, spread via Central Asia to form the other main ancestral population.The Steppe ancestry in South Asia has the same profile as that in Bronze Age Eastern Europe, tracking a movement of people that affected both regions and that likely spread the distinctive features shared between Indo-Iranian and Balto-Slavic languages.
Format du dépôt | Notice |
---|---|
Type de dépôt | Article dans une revue |
Résumé |
en
By sequencing 523 ancient humans, we show that the primary source of ancestry in modern South Asians is a prehistoric genetic gradient between people related to early hunter-gatherers of Iran and Southeast Asia. After the Indus Valley Civilization’s decline, its people mixed with individuals in the southeast to form one of the two main ancestral populations of South Asia, whose direct descendants live in southern India. Simultaneously, they mixed with descendants of Steppe pastoralists who, starting around 4000 years ago, spread via Central Asia to form the other main ancestral population.The Steppe ancestry in South Asia has the same profile as that in Bronze Age Eastern Europe, tracking a movement of people that affected both regions and that likely spread the distinctive features shared between Indo-Iranian and Balto-Slavic languages.
|
Titre |
en
The Genomic Formation of South and Central Asia
|
Auteur(s) |
Gheesh Narasimhan
, Nick Patterson
1
, Priya Moorjani
2
, Nadin Rohland
3
, Nicole Boivin
4
, Kumarasamy Thangaraj
5
, Julio Bendezu-Sarmiento
6
, David Reich
1
1
BROAD INSTITUTE -
Broad Institute of MIT and Harvard
( 38338 )
- Cambridge, MA 02142
- États-Unis
2
HMS -
Harvard Medical School [Boston]
( 130467 )
- 25 Shattuck Street Boston, MA 02115
- États-Unis
3
Harvard School of Public Health
( 408186 )
- 665 Huntington Ave, Boston, MA 02115
- États-Unis
4
MPI-SHH -
Max Planck Institute for the Science of Human History
( 527959 )
- Kahlaische Str. 10, 07745 Jena, Germany
- Allemagne
5
CCMB -
CSIR - Centre for Cellular and Molecular Biology
( 454219 )
- Uppal Road, Habsiguda, Hyderabad, Telangana 500007, Inde
- Inde
6
EAE -
Eco-Anthropologie et Ethnobiologie
( 117740 )
- Dpt Hommes Natures Sociétés, 57 rue Cuvier 75231 Paris Cedex 05 -
Musée de l'Homme, place du Trocadéro 75016 Paris
- France
|
Nom de la revue |
|
Date de publication |
2019-09
|
Audience |
Internationale
|
Comité de lecture |
Oui
|
Vulgarisation |
Non
|
Langue du document |
Anglais
|
Domaine(s) |
|
DOI | 10.1126/science.aat7487 |
PubMed Central | PMC6822619 |
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