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HLA-DRB1 frequencies of the comorian population and their genetic affinities with sub-saharian African and indian oceanian populations

Abstract : Ethnic-historic sources have considered the Comorian population to be the result of an amalgamation of African, Arabian and Southeast Asian groups. AIM: This study seeks to determine the genetic relationships and contributions from Sub-Saharan Africa and Indian Oceania and to reconstruct past migration events. SUBJECTS AND METHODS: The human leukocyte antigen (HLA) polymorphism of a Comorian population was described and analysed. RESULTS: Genetic distances and multidimensional scaling analyses showed complex patterns of genetic differentiation in the Indian Oceanian area as a result of continuous gene flow occurring within the past approximately 2500 years. Nevertheless, the Comorian genetic pool appears to be a mix of Bantu-speaking and Arab populations as testified to by admixture estimations of almost 50-60% and 27-33%, respectively. CONCLUSION: The Comorian population may represent the eastern limit of the recent and massive eastward Bantu expansion. In contrast to the population from Madagascar (Merina), only a restricted influence of Austronesian populations was found.
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https://halshs.archives-ouvertes.fr/halshs-03007237
Contributor : Morgane Gibert <>
Submitted on : Monday, November 16, 2020 - 11:50:59 AM
Last modification on : Monday, March 29, 2021 - 10:32:04 AM

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Morgane Gibert, Mhammed Touinssi, Denis Reviron, Pierre Mercier, Gilles Boëtsch, et al.. HLA-DRB1 frequencies of the comorian population and their genetic affinities with sub-saharian African and indian oceanian populations. Annals of Human Biology, Taylor & Francis, 2006, 33 (3), pp.265-278. ⟨halshs-03007237⟩

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