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L'apoptose modifie-t-elle les concepts de milieu intérieur et de régulation ?

Abstract : There is an asymmetry between life and death: life is first, death is second. The programmed cell death, apoptosis or cell suicide, involves activation, which is caused by life, not death. To say that death is at the heart of life does not mean that it is the cause, or even that it is the secret engine of evolution. Even if the onset of cell suicide leads to the death of the cell, to speak of death as if it were an entire organism may expose us, if we forget it, to a sort of vitalism of death. The history of the concept of regulation, which contains analytically that of regulated cell death, reminds us of the danger that sometimes consists in exceeding the limits of a model metaphorically or philosophically. This story also reminds us that biological causality is most often indirect, selectionist. To imagine a direct action of death on life would be to forget this way of acting proper to life.
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Nicolas Aumonier. L'apoptose modifie-t-elle les concepts de milieu intérieur et de régulation ?. Laurent Cherlonneix, avec la participation de Jean-Claude Ameisen. Nouvelle représentation de la vie en biologie et philosophie du vivant. La "Sculpture du vivant" à la lumière de l'interdisciplinarité, Editions De Boeck Université, chapitre 3, pp. 73-88, 2013, 9782804169008. ⟨halshs-01998358⟩

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