Indicators of Benzodiazepine Use in Nursing Home Residents in France: A Cross-Sectional Study

Philippe Barreto de Souto (1, 2) , Céline Mathieu , Christine Piau (3) , Maryse Lapeyre-Mestre (4) , Catherine Bouget (3) , Françoise Cayla , Bruno Vellas (2) , Yves Rolland (2)

1 ADES - Anthropologie bio-culturelle, Droit, Ethique et Santé
2 Gérontopôle
3 Agence Reg Sante, Midi Pyrenees, France
4 Service Pharmacologie Clinique [CHU Toulouse]

Objectives: Little information is available about associations between nursing home (NH) structural and organizational aspects and benzodiazepine prescriptions, particularly for long-acting drugs. This study addressed this knowledge gap. Design: Cross-sectional study. Setting: One hundred seventy-five NHs from France. Participants: A total of 6275 NH residents, aged 86 years (+/- 8.2), and mostly women (73.7%). Measurements: Outcome measures were: (1) benzodiazepine and (2) long-acting benzodiazepine use. NH staff sent to research team all drug prescriptions in the week participants were included in the study; staff also recorded information on residents' characteristics, and NHs structure and internal organization. Binary logistic regressions were performed separately on total and long-acting benzodiazepine. Results: A total of 3350 persons took benzodiazepine; 577 took long-acting benzodiazepine. Subject-related characteristics were the main correlates of benzodiazepine use. NH characteristics were also related to this outcome: number of beds >= 91 (Odds Ratio (OR) 0.820, 95% Confidence Interval (CI) 0.682-0.986), special care unit (OR 1.131, 95% CI 1.000-1.279), pharmacy for internal usage (OR 1.341, 95% CI 1.128-1.594), and date records of the first prescription of psychotropics (OR 1.394, 95% CI 1.209-1.607). Pharmacy for internal usage was also associated with long-acting benzodiazepine (OR 1.374, 95% CI 1.076-1.754). Conclusions: NH structure-and organization-related indicators impact benzodiazepine use among NH residents. This finding is of particular importance because these indicators are more easily modifiable than subject-related characteristics. Therefore, NH directors and medical staff should be aware about this to implement feasible modifications for reducing inappropriate and chronic benzodiazepine use

Mots clés: Psychotropic; older adults; nursing home; dementia

Domaines: Anthropologie biologique

Philippe Barreto de Souto, Céline Mathieu, Christine Piau, Maryse Lapeyre-Mestre, Catherine Bouget, et al.. Indicators of Benzodiazepine Use in Nursing Home Residents in France: A Cross-Sectional Study. Journal of the American Medical Directors Association, 2013, 14 (1), pp.29-33. ⟨10.1016/j.jamda.2012.09.002⟩. ⟨halshs-00847487⟩