A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe

Natalie Myres (1) , Siiri Rootsi (2, 3) , Alice Lin (4) , Jaerve Mari (2, 3, 4) , Roy J. King (4) , Jacques Chiaroni (1, 5) , Cristofaro Julie Di (1, 5) , Peter Underhill (4)

1 Sorenson Molecular Genealogy Foundation
2 Dept Evolutionary Biol,
3 Estonian Bioctr,
4 Department of Psychiatry and Behavioral Sciences [Stanford]
5 UAABC - Anthropologie Bio-Culturelle

The phylogenetic relationships of numerous branches within the core Y-chromosome haplogroup R-M207 support a West Asian origin of haplogroup R1b, its initial differentiation there followed by a rapid spread of one of its sub-clades carrying the M269 mutation to Europe. Here, we present phylogeographically resolved data for 2043 M269-derived Y-chromosomes from 118 West Asian and European populations assessed for the M412 SNP that largely separates the majority of Central and West European R1b lineages from those observed in Eastern Europe, the Circum-Uralic region, the Near East, the Caucasus and Pakistan. Within the M412 dichotomy, the major S116 sub-clade shows a frequency peak in the upper Danube basin and Paris area with declining frequency toward Italy, Iberia, Southern France and British Isles. Although this frequency pattern closely approximates the spread of the Linearbandkeramik (LBK), Neolithic culture, an advent leading to a number of pre-historic cultural developments during the past <= 10 thousand years, more complex pre-Neolithic scenarios remain possible for the L23(xM412) components in Southeast Europe and elsewhere

Mots clés: Y-chromosome; haplogroup R1b; human evolution; population genetics

Domaines: Anthropologie biologique

Natalie Myres, Siiri Rootsi, Alice Lin, Jaerve Mari, Roy J. King, et al.. A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe. European Journal of Human Genetics, 2011, 19 (1), pp.95-101. ⟨10.1038/ejhg.2010.146⟩. ⟨halshs-00738166⟩