Distribution of haemophilia in the French Basque country.

Frédéric Bauduer (1) , Anna Degioanni (1) , Louis Ducout (2) , Cédric Scribans (3) , Olivier Dutour (1)

1 UAABC - Anthropologie Bio-Culturelle
2 Department of Hematology
3 Biostatistics

Because peculiar profiles for some genetic haematological diseases have been described among Basques, we aimed to investigate the distribution of haemophilia among this specific population. Hence, we retrospectively assessed all the cases of factor (F) VIII and FIX deficiencies seen in the French Basque country during a 16-year period. Data on 41 patients with haemophilia (FVIII or FIX ¼ 25%) were compiled. Incidence and prevalence for the whole population ranged within the classical limits (but with an unusually high A : B ratio) and tended to be slightly lower in autochthonous Basques (P ¼ n.s.). Our data did not support significant differences in the distribution of this disease among French Basques

Mots clés: population genetics; Basques; haemophilia; population genetics.

Domaines: Anthropologie biologique

Frédéric Bauduer, Anna Degioanni, Louis Ducout, Cédric Scribans, Olivier Dutour. Distribution of haemophilia in the French Basque country.. Haemophilia, 2002, 8, pp.735-739. ⟨halshs-00637769⟩